MP 26 Pill: Side Effects, Dosage, Uses, and More

amitriptyline hydrochloride
amitriptyline hydrochloride

The pill with imprint MP 26 is Brown, Round and has been identified as Amitriptyline Hydrochloride 50 mg. It is supplied by Mutual Pharmaceutical Company, Inc.

This drug is used to treat mental/emotional issues including depression. It may help you boost your mood and sense of well-being, decrease worry and tension, sleep better, and have more energy. This drug belongs to the tricyclic antidepressant class of pharmaceuticals. It works by changing the balance of certain natural chemicals in the brain (neurotransmitters like serotonin).

amitriptyline hydrochloride

What Are The Uses of MP 26 Pill (Amitriptyline)?

Amitriptyline is available as a tablet for oral use. It’s typically taken one to four times each day. Every day, take amitriptyline at the same time(s). Follow the instructions on your prescription label exactly, and ask your doctor or pharmacist to explain any parts you don’t understand. Amitriptyline should be taken exactly as prescribed. Do not take more or less of it, or take it more frequently than your doctor has suggested.

Your doctor will most likely begin you on a low dose of amitriptyline and gradually increase it.

It may take several weeks or more to feel the full effects of amitriptyline. Even if you feel OK, keep taking amitriptyline. Do not discontinue amitriptyline without first consulting your doctor. If you stop taking amitriptyline abruptly, you may have withdrawal symptoms such as nausea, headache, and fatigue. Your doctor will most likely progressively reduce your dose.

Other uses for this medicine

In addition to its usage in the treatment of eating disorders, amitriptyline is also prescribed for the prevention of migraine headaches, post-herpetic neuralgia (the aching, burning, or throbbing symptoms that can last for months or even years following a shingles infection), and post-herpetic neuralgia. Have a discussion with your primary care physician about the potential side effects of taking this medicine to treat your condition.

It is possible that your doctor will prescribe this medicine for a purpose other than what is described here; please consult with them for further information.

What Are The Side Effects of MP 26 Pill (Amitriptyline)?

There is a possibility that amitriptyline will cause side effects. Inform your physician if any of the following symptoms persist for an extended period of time or are particularly severe:

Serious side effects

There are several side effects that might be quite serious. Immediately contact your physician if you encounter any of the following symptoms, as well as any of the ones indicated in the section labeled “IMPORTANT WARNING”:

  • slow or difficult speech
  • dizziness or faintness
  • weakness or numbness of an arm or a leg
  • crushing chest pain
  • rapid, pounding, or irregular heartbeat
  • severe skin rash or hives
  • swelling of the face and tongue
  • yellowing of the skin or eyes
  • jaw, neck, and back muscle spasms
  • uncontrollable shaking of a part of the body
  • fainting
  • unusual bleeding or bruising
  • seizures
  • hallucinating (seeing things or hearing voices that do not exist)

Overdose Symptoms of MP 26 Pill (Amitriptyline)

Symptoms of overdose may include:

  • irregular heartbeat
  • seizures
  • coma (loss of consciousness for a period of time)
  • confusion
  • problems concentrating
  • hallucinating (seeing things or hearing voices that do not exist)
  • agitation
  • drowsiness
  • rigid muscles
  • vomiting
  • fever
  • cold body temperature

Amitriptyline Interaction with other medications

There is a possibility of an interaction occurring between the oral tablet form of amitriptyline and any other drugs, vitamins, or herbs that you could be taking. When one substance alters the functioning of another, this is known as an interaction. This may result in adverse effects or reduce the efficacy of the medication.

Your physician ought to properly manage all of your prescriptions for you in order to help you avoid interactions. It is imperative that you discuss any drugs, supplements, or herbs that you are currently taking with your primary care physician. Talk to your healthcare provider or pharmacist if you have any questions about how this medication might interact with other medications that you are currently taking.

The following is a list of certain medications that, when combined with amitriptyline, may result in undesirable side effects.

Drugs you should not take with amitriptyline

Combining amitriptyline with other medications may increase the side of experiencing side effects. It is not a good idea for you to take these other medications along with the amitriptyline. Some examples of these medications are as follows:

  • Monoamine oxidase inhibitors (MAOIs). Examples of these drugs include:
    • phenelzine
    • tranylcypromine
    • selegiline

Combining amitriptyline and an MAOI could potentially result in seizures or even death. If your doctor has not instructed you otherwise, you should wait at least two weeks after quitting amitriptyline before starting an MAOI. If you have stopped taking an MAOI within the past two weeks, do not begin taking amitriptyline unless your primary care physician specifically instructs you to do so. Ask your physician or pharmacist if you are unsure about whether or not any of the medications you are currently taking contains an MAOI.

  • Quinidine. It’s possible that taking this medication alongside amitriptyline will cause your body to produce more of the latter. This could result in certain potentially harmful side effects.

Drugs that cause more negative effects

Combining amitriptyline with certain other medications raises the probability of adverse consequences occurring. Some examples of these medications are as follows:

  • Topiramate. Taking this drug with amitriptyline could increase the amount of amitriptyline in your body. This raises your risk of side effects. Your doctor may adjust your dosage of amitriptyline if you take it with topiramate.
  • Sertraline, fluoxetine, and paroxetine. These drugs can increase the dangerous side effects of amitriptyline.
  • Cimetidine. Taking this drug with amitriptyline could increase the amount of amitriptyline in your body. This raises your risk of side effects.
  • Anticholinergic drugs. Examples include diphenhydramineoxybutyninsolifenacin, and olanzapine. Taking these drugs with amitriptyline raises your risk of side effects such as fever, especially during hot weather.
  • Neuroleptic drugs. Examples include clozapinerisperidone, and haloperidol. Taking these drugs with amitriptyline raises your risk of side effects such as fever, especially during hot weather.

Amitriptyline Dosage

All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:

  • your age
  • the condition being treated
  • the severity of your condition
  • other medical conditions you have
  • how you react to the first dose

Forms and strengths

Generic: Amitriptyline

  • Form: oral tablet
  • Strengths: 10 mg, 25 mg, 50 mg, 75 mg, 100 mg, 150 mg

Dosage for depression

Adult dosage (ages 18–64 years)

  • Typical starting dosage: 75 mg per day, usually in divided doses.
  • Dosage increases: Your doctor will slowly increase your dosage if needed.
  • Maximum dosage: 150 mg per day.
  • Alternative dosage regimen: Start with 50 to 100 mg at bedtime. This may be increased by 25 or 50 mg as needed in the bedtime dose, for a total of 150 mg per day.

Child dosage (ages 12–17 years)

Typical starting dosage: 10 mg three times a day with 20 mg at bedtime, for a total of 50 mg per day.

Child dosage (ages 0–11 years)

It hasn’t been confirmed that amitriptyline is safe and effective for use in children younger than 17 years.

Senior dosage (ages 65 years and older)

It’s possible that kidney function declines with age, particularly in elderly persons. This may result in a decreased rate of medication elimination from your body. As a consequence of this, a greater quantity of a medicine is retained in your body for a longer period of time. This increases the likelihood that you will experience side effects.

It’s possible that your primary care physician will start you out on a lower dose or a different dosing regimen. This can help prevent dangerously high quantities of this substance from developing inside of your body in the first place.


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